Introducing Fluorine to Biotechnology
The ambition of SinFonia is to set the stage for a future economically, ecologically and societally sustainable value chain for the production of novel, bio-based fluoropolymers from renewable substrates. The innovation potential of SinFonia is high: we have set several ground-breaking objectives that include cutting-edge synthetic biology, smart metabolic engineering, rational protein design, bioprocess engineering, material science and polymer chemistry. Our project will contribute concepts and approaches to these fields (including standardization of metabolic pathways from difficult-to-manipulate organisms to ease their transfer into a formatted and robust bacterial chassis) while designing cell factories for efficient synthesis of novel fluorinated products.